The use of a urethral catheter with an ultrasound-induced biopolymer drug coating for the prevention of recurrent bladder neck sclerosis in patients after endoscopic treatment of benign prostate hyperplasia

Kamalov A.A., Sorokin N.I., Kadrev A.V., Shaparov B.M., Afanasevskaya E.V., Sindeeva O.A., Sukhorukov G.B., Kritsky A.A., Pyataev N.A., Abdurashitov A.S., Kulikov O.A., Proshin P.I.

1) Urology and Andrology Branch, Faculty of Fundamental Medicine, Lomonosov Moscow State University, Moscow, Russia; 2) Department of Urology and Andrology, Lomonosov MSU Medical Research and Educational Center, Moscow, Russia; 3) A.V. Zelmann Center for Neurobiology and Brain Rehabilitation, Skolkovo Institute of Science and Technology, Moscow, Russia; 4) LLC Magnetic Drug Delivery, AMT & C Group, Moscow, Russia; 5) Institute of Medicine, National Research Ogarev Mordovia State University, Saransk, Russia; 6Moscow City Clinical Hospital No. 17, Moscow, Russia; 7Istra Regional Clinical Hospital, Istra, Russia

Recurrent bladder neck sclerosis is one of the common complications of endoscopic treatment of benign prostate hyperplasia, which often leads to multiple re-operations, including complex open and laparoscopic reconstructive procedures. One of the most promising minimally invasive methods for preventing recurrence of bladder neck sclerosis is balloon dilatation under transrectal ultrasound guidance. To improve the results of using this technique, a urethral catheter with a biopolymer coating, capable of depositing a drug and eluting it under the influence of diagnostic ultrasound, was proposed.

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About the Authors

Corresponding author: B.M. Shaparov – urologist at the Urologic Department of the GBUZ City Clinical Hospital No. 17 of Moscow Healthcare Department, Moscow, Russia; e-mail: uroboris@mail.ru

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