Antioxidants and micronutrients for the prevention and correction of reproductive dysfunction in men, the role of polyunsaturated fatty acids: a review of studies

Korneyev I.A.

1) Federal State Budgetary Educational Institution of Higher Education «Pavlov First Saint Petersburg State Medical University», Saint Petersburg, Russia; 2) International Centre for reproductive medicine, Saint Petersburg, Russia

The review article reflects current opinion in oxidative stress impact on male fertility, as well as the possibilities of restoring redox balance and normalizing reproductive function by administration of substances with antioxidant properties and products containing polyunsaturated fatty acids. The review covers Russian studies of antioxidant complexes «BESTFertil», which includes L-Carnitine, L-Arginine, Vitamin C and E, Folic Acid, Zinc, Selenium, Glutathione and Coenzyme Q10 and Ginseng Root Extract, as well as «BESTFertil-DHA», supplemented with capsules with Omega-3 polyunsaturated fatty acids. These studies resulted in increase of basic semen parameters - concentration, motility and proportion of normal forms of spermatozoa, as well as in decrease in sperm DNA fragmentation.

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About the Authors

Corresponding author: I.A. Korneyev – Dr.Med.Sci., professor of the department of urology Pavlov First Saint Petersburg State Medical University», Chief physician "International center for reproductive medicine", Saint Petersburg, Russia; e-mail: iakorneyev@yandex.ru

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