ISSN 1728-2985
ISSN 2414-9020 Online

Typical patient models for conservative therapy of male infertility. Pathogenetic approaches and expected effects

Epanchintseva E.A., Selyatitskaya V.G.

1) Federal research center of fundamental and translational medicine, Novosibirsk, Russia; 2) LLC «Novosibirsk center of reproductive medicine» GK «Mother and child», Novosibirsk, Russia; 3) Novosibirsk State Medical University of the Ministry of Health of Russia, Novosibirsk, Russia
Male infertility may be a consequence of various diseases, many of which can be detected during examination. Modern methods of treating male infertility are diverse and include drug and non-drug therapy, diet therapy, and also a combination therapy that combines them, and therefore choosing the optimal approach to each patient is an absolutely important task. We have analyzed the literature on approaches to treating patients with different hormonal status, which allows us to conclude that hormonal therapy in certain cases has a positive effect on spermatogenesis parameters and increases the chance of pregnancy, but at the same time, it is necessary to systematize the available data to identify typical patient models for conservative therapy of male infertility.

Keywords

male infertility
hypogonadism
gonadotropins
selective estrogen receptor modulators
aromatase inhibitors
nutritional therapy
antioxidant therapy
L-carnitine
acetyl-L-carnitine

About the Authors

Corresponding author: E.A. Epanchintseva – candidate of medical sciences, senior researcher at the laboratory of endocrinology Federal research center of fundamental and translational medicine, assistant professor of the department of urology Novosibirsk state medical university of the ministry of health of the Russian Federation, endocrinologist-andrologist LLC «Novosibirsk center of reproductive medicine» GK «Mother and child», Novosibirsk, Russia; е-mail: epane@yandex.ru

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