Оfeatures of ultrastructural and molecular-cellular manifestations of pyelo-nephritis

Berdichevsky B.A., Gonyaev A.R., Boldyrev A.L., Zubik G.V., Garagashev G.G., Uchaev D.A., Korabelnikov M.A.

1) Urology Clinic, Tyumen State Medical University of the Russian Ministry of Health, Tyumen, Russia; 2) Mother and Child Clinical Hospital, Tyumen, Russia; 3) Nanotechnology Research and Education Center, South Ural State University of the Russian Ministry of Health, Chelyabinsk, Russia; 4) Medical Center «Medical City», Tyumen, Russia

Three clinical observations in patients with various manifestations of pyelonephritis are presented. Using 18F-FDG PET/CT and transmission electron microscopy of the renal parenchyma at 10,000x magnification, the ultrastructural and molecular-cellular features of acute purulent pyelonephritis, chronic pyelonephritis with neurogenic hypertension, and chronic pyelonephritis resulting in secondary contracted kidney are identified. The clinical significance of the identified changes, the reliability of the obtained results, and the prospects for their further application are discussed.

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About the Authors

Corresponding author: B.A. Berdichevsky – MD, PhD, Professor, Professor of the Department of Pediatric Surgery with a Course in Urology and Andrology at Tyumen State Medical University of the Russian Ministry of Health, Tyumen, Russia; e-mail: doktor_bba@mail.ru

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