Multiple schwannoma of the scrotum: a clinical case

Boshchenko V.S., Mikhailovskiy D.M., Krakhmal N.V., Vtorushin S.V.

1) Siberian State Medical University, Ministry of Health of Russia, Tomsk, Russia; 2) Cancer Research Institute, Tomsk National Research Medical Center of the Russian Academy of Sciences, Tomsk, Russia

Schwannoma is a benign tumor arising from the peripheral nerve sheaths and consisting of highly differentiated Schwann cells, which under physiological conditions produce the essential component of nerve fibers myelin. Frequent localization of neoplasms are areas with developed and abundant nerve supply – the head, neck, limbs, less often its occur in the chest, mediastinum, retroperitoneum, adrenal glands, organs of the gastrointestinal tract, cases of schwannoma of the penis and vulva are also described. In clinical practice, extratesticular schwannoma of the scrotum is extremely rare, when analyzing literary sources, descriptions of only isolated observations were found. Scrotal schwannoma is often associated with systemic pathology – neurofibromatosis type 2 or schwannomatosis, isolated development of the tumor is rather considered an exceptional event. In this article, we present a description of a clinical case of multiple large scrotal schwannoma in a 45-year-old man who underwent surgical treatment with excision of the tumor in 2011. During the period 2011–2024, the patient had no relapse of the disease, the quality of life was high and the prognosis was favorable.

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About the Authors

Corresponding author: N.V. Krakhmal – Cand.Med.Sci., Assistant of Professor of the Pathology Department of Federal State Budgetary Educational Institution of Higher Education «Siberian State Medical University»; Senior Researcher of the Department of General and Molecular Pathology Cancer Research Institute – Tomsk National Research Medical Center Russian Academy of Sciences; Tomsk, Russia; e-mail: krakhmal@mail.ru

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